NEW YORK, March 28, 2012 /PRNewswire/ -- S&P MidCap 400 constituent Fossil, Inc. (NASD: FOSL) will replace Medco Health Solutions, Inc. (NYSE: MHS) in the S&P 500 index, S&P SmallCap 600 constituent BioMed Realty Trust, Inc. (NYSE: BMR) will replace Fossil in the S&P MidCap 400 index, and Innophos Holdings, Inc. (NASD: IPHS) will replace BioMed Realty Trust in the S&P SmallCap 600 index after the close of trading on a date to be announced.  S&P 500 constituent Express Scripts, Inc. (NASD: ESRX)  is acquiring Medco Health Solutions in a deal expected to be completed soon pending final approvals.

Fossil designs, develops, markets, and distributes consumer fashion accessories. Headquartered in Richardson, TX, the company will be added to the S&P 500 GICS (Global Industry Classification Standard) Apparel Accessories & Luxury Goods Sub-Industry index.

BioMed Realty Trust is a real estate investment trust (REIT) that provides real estate to the life science industry.  Headquartered in San Diego, CA, the company will be added to the S&P MidCap 400 GICS Office REITs Sub-Industry index.

Innophos Holdings engages in the production of mineral based specialty ingredients. Headquartered in Cranbury, NJ, the company will be added to the S&P SmallCap 600 GICS Specialty Chemicals Sub-Industry index.

Following is a summary of the changes:

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