NEW YORK, Oct. 6, 2022 /PRNewswire/ -- S&P MidCap 400 constituent Targa Resources Corp. (NYSE:TRGP) will replace Nielsen Holdings plc (NYSE:NLSN) in the S&P 500, S&P SmallCap 600 constituent Lantheus Holdings Inc. (NASD:LNTH) will replace Targa Resources in the S&P MidCap 400, and Payoneer Global Inc. (NASD:PAYO) will replace Lantheus Holdings in the S&P SmallCap 600 effective prior to the opening of trading on Wednesday, October 12. Elliot Management Corp is acquiring Nielsen Holdings in a transaction expected to close October 11.

Following is a summary of the changes that will take place prior to the open of trading on the effective date:

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